Apolioprotein A1 (APOA1) antibody

Antigen: Apolioprotein A1 (APOA1)

Synonyms: Sep2, Alp-1, Ltw-1, Sep-1, Sep-2, Apoa-1, Brp-14, Lvtw-1, MGC102525, apoA-I, apoa, cb49, MGC103718, wu:fb33f01, zgc:103718, APOA1, MGC64335, MGC89745, LOC100009253, ApoA-I, LOC100136573, apoa1, MGC117399, apoa-i

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus), Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN361201

Additional Information

Alternative name: Apolipoprotein A-1, APOA1

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human APOA1, different to the related mouse sequence by two amino acids

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. 1 The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. 2 The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. 3 Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport. 4

Synonyms: Sep2, Alp-1, Ltw-1, Sep-1, Sep-2, Apoa-1, Brp-14, Lvtw-1, MGC102525, apoA-I, apoa, cb49, MGC103718, wu:fb33f01, zgc:103718, APOA1, MGC64335, MGC89745, LOC100009253, ApoA-I, LOC100136573, apoa1, MGC117399, apoa-i

Application Details

Application Notes: Recommended Dilutions: WB 1ug/ml

Purification: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Restrictions: For Research Use only

Images

anti-Apolioprotein A1 (APOA1) antibody