CD82 (CD83) antibody
| Antigen |
|
| Synonyms |
BL11, HB15, R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
|
| Catalog no. |
ABIN361202 |
| Quantity |
100ug |
| Price |
283.33 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 5 to 7 Business Days |
|
Alternative name
|
CD82
|
|
Immunogen
|
A synthetic peptide corresponding to a sequence at the C-terminal of human CD82, different to the related mouse sequence by two amino acids
|
|
Format
|
Affinity-purified
|
|
Isotype
|
IgG (Matching secondary antibodies)
|
|
Description
|
CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene.The gene is mapped to 11p11.2. 1 This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. 2 The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). 3 And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1. 4
|
|
Application Notes
|
Recommended Dilutions: WB 1ug/ml
|
|
Purification
|
Immunogen affinity purified.
|
|
Buffer
|
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .
|
|
Storage
|
Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.
|
|
Research Area
|
Cancer, Transcription Factors, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "CD82 (CD83)", type "Antibodies"
|
Hosts
|
Mouse (41), Rabbit (11), Rat (5)
|
|
Reactivities
|
Human (50), Mouse (Murine) (8), Primate (3), Rat (Rattus) (2)
|
|
Applications
|
Flow Cytometry (FACS) (35), Western Blotting (WB) (19), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Immunohistochemistry (IHC) (6), ELISA (3), ELISA (Detection) (3), Immunofluorescence (IF) (2), Immunoprecipitation (IP) (1)
|
|
Conjugates
|
FITC (7), PE (6), Biotin (4), RPE (1)
|
|
Epitopes
|
C-Term (3)
|