Lipoprotein Lipase (LPL) antibody

Antigen: Lipoprotein Lipase (LPL)

Synonyms: LIPD, HDLCQ11, MGC93586, fb62e04, fc49b03, wu:fb62e04, wu:fc49b03, LPL, MGC137861, lipd, hdlcq11, Lpl, lpl, LOC100223817

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Rat (Rattus), Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN361206

Additional Information

Alternative name: Lipoprotein lipase, LPL

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human LPL, different to the related rat sequence by two amino acids

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion.

Application Details

Application Notes: Recommended Dilutions: WB 1ug/ml

Purification: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Restrictions: For Research Use only

Images

anti-Lipoprotein Lipase (LPL) antibody