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Antibodies
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anti-Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody
Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody
| Antigen |
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| Synonyms |
GEFSP1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361210 |
| Quantity |
100ug |
| Price |
283.33 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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Sodium channel, voltage-gated, beta 1, SCN1B
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Immunogen
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A synthetic peptide corresponding to a sequence at the N-terminal of human SCN1B, identical to the related rat and mouse sequence
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Format
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Affinity-purified
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Voltage-gated sodium (Na+) channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. The complete coding region of Sodium channel, voltage-gated, beta 1(SCN1B) is found in approximately 9.0 kb of genomic DNA and consists of five exons (72 to 749 bp) and four introns (90 bp to 5.5 kb). It is mapped to 19q13.1 and can act as a candidate gene for hereditary disorders affecting membrane excitability. 1 Sodium channel beta1 subunits play important roles in the regulation of sodium channel density and localization and are involved in axo-glial communication at nodes of Ranvier. 2
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Application Notes
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Recommended Dilutions: WB 1ug/ml
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Purification
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Immunogen affinity purified.
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Buffer
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Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .
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Storage
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Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.
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Restrictions
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For Research Use only
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Alternatives for antigen "Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)", type "Antibodies"
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Hosts
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Rabbit (23)
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Reactivities
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Human (22), Mouse (Murine) (19), Rat (Rattus) (19), Cow (Bovine) (2), Dog (Canine) (2), Horse (Equine) (2), Pig (Porcine) (2)
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Applications
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Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (6), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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