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Characteristics
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Positive control: Hela.
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Swiss-Prot
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Q13509/Q9ERD7
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Immunogen
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This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to the near of N-terminal residues of neuro-specific class III -tubulin.
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Format
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Liquid
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Isotype
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IgG2a (Matching secondary antibodies)
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Clone
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A8-D10
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Description
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Tubulin is a compound of subunits of A tubulin and B tubulin. Class III beta tubulin (beta III-tubulin) is a vertebrate tubulin isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class III beta tubulin is associated with the resistances of microtubule-targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors.
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Specificity
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Cellular Localization: Database linksMolecular Weight: 50kDa
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Molecular Weight
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50kDa
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