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LT-alpha (TNF-beta) antibody
| Antigen | LT-alpha (TNF-beta) |
| Clonality | Monoclonal (C2-F2) |
| Host |
Mouse |
| Reactivity |
Human |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN361243 |
| Quantity | 100ul (0.56mg/ml) |
| Price | 350.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics |
Positive control: Recombinant LT-alpha(TNF-). Cellular Localization: Secretory protein |
| Swiss-Prot | P01374 |
| Immunogen | This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of LT-alpha. |
| Cross-Reactivity | Human, Mouse (Murine), Rat (Rattus) |
| Format | Liquid |
| Isotype | IgG2b (Matching secondary antibodies) |
| Clone | C2-F2 |
| Description | Lymphotoxin-alpha (LTA), a member of the tumor necrosis factor (TNF) family of cytokines, was initially isolated on the basis of an anti-tumor activity. LTA plays a key role in communication between lymphocytes and stromal cells, thereby eliciting cytotoxic effects on cancer cells. It induces the expression of vascular cell-adhesion molecule 1 (VCAM1) on vascular endothelial cells and recruits natural killer (NK) cells to parenchymal organs and tumor lesions. |
| Specificity | Cellular Localization: Secretory protein. Molecular Weight: 18kDa |
| Molecular Weight | 18kDa |
