CD44 (CD44) antibody

Antigen: CD44 (CD44)

Synonyms: IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, MUTCH-I, ECMR-III, MGC10468

Clonality: Monoclonal (A7-1)

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN361251

Additional Information

Alternative name: CD44

Swiss-Prot: P16070

Immunogen: This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to the residues of human CD44.

Format: Liquid

Clone: A7-1

Description: CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing and tumor-cell metastasis. It mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications

Specificity: Cellular Localization: cytoplasmic membrane. Molecular Weight: 80-250kDa

Application Details

Application Notes: Recommended Dilutions: WB: 1:500-1:1000. Positive Control: Hela cells

Concentration: 0.5mg/ml

Purification: Immunogen affinity purified

Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Storage: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Research Area: Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Cancer, Cell Cycle

Restrictions: For Research Use only

Images

Western blot analysis on Hela using anti-CD44 monoclonal antibody. CD44