tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, beta Polypeptide (YWHAB) antibody

Antigen: tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, beta Polypeptide (YWHAB)

Synonyms: HS1, GW128, KCIP-1, 1300003C17Rik, ywhab, MGC53093, MGC78918, 14-3-3beta, hs1, gw128, kcip-1, YWHAB, 1433b, DKFZp459L1720

Clonality: Monoclonal (9-26)

Host: Mouse

Application: Western Blotting (WB)

Catalog no.: ABIN361254

Additional Information

Alternative name: 14-3-3ba

Swiss-Prot: Q9CQV8 (mouse)

Immunogen: This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of 14-3-3b/a protein.

Format: Liquid

Clone: 9-26

Description: The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner

Specificity: Cellular Localization: Cytoplasm, Melanosome. Molecular Weight: 28kDa

Application Details

Application Notes: Recommended Dilutions: WB: 1:1000-1:2000. Positive Control: Mouse liver

Concentration: 0.5mg/ml

Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.

Storage: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Restrictions: For Research Use only

Images

Western blot analysis on mouse liver lysates using anti-14-3-3 b/a monoclonal antibody. 14-3-3 b/a