Chromogranin-A antibody
| Antigen |
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| Clonality |
Monoclonal (D11-4) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361259 |
| Quantity |
100ul (0.43mg/ml) |
| Price |
350.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Positive control: PC12. Cellular Localization: Secretary protein
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Swiss-Prot
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P10645
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Immunogen
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This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of Chromogranin A.
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Format
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Liquid
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Isotype
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IgG2a (Matching secondary antibodies)
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Clone
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D11-4
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Description
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Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes
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Specificity
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Cellular Localization: Secretory protein. Molecular Weight: ~86kDa
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Molecular Weight
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~86kDa
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Application Notes
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WB: 1:2,000
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Concentration
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0.43mg/ml
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Buffer
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1xTBS (pH7.4), 0.5%BSA, 25%Glycerol.
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Preservative
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0.05% Sodium Azide.
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Storage
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Store at +4° C after thawing. Aliquot store at -20° C or -80° C. Avoid repeated freeze / thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "Chromogranin-A", type "Antibodies"