Synapsin I (SYN1) antibody
| Antigen |
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| Synonyms |
SYNI, SYN1a, SYN1b, Syn-1, MGC152080, SYN I, Synapsin-1, LOC570672, SYN1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361410 |
| Quantity |
50 µl (Variants) |
| Price |
295.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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Synapsin I
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Description
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Synapsin I plays a key role in synaptic plasticity in the brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989, Stone et al., 1994). Thus, Synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Anti-Synapsin I Western blot of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein.
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Specificity
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Specific for the ~78k synapsin I protein doublet. Immunolabeling blocked by preadsorption of the antibody with the protein used to generate the antibody.
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Application Notes
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Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
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Purification
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Unpurified neat serum.
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Storage
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Store at -20 °C, stable for 1 year
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Research Area
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Neurology
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Restrictions
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For Research Use only
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Alternatives for antigen "Synapsin I (SYN1)", type "Antibodies"
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Hosts
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Rabbit (47), Mouse (6)
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Reactivities
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Human (38), Rat (Rattus) (33), Mouse (Murine) (29), Cow (Bovine) (14), Xenopus laevis (5), Dog (Canine) (2), Monkey (1)
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Applications
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Western Blotting (WB) (50), Immunofluorescence (IF) (14), Immunohistochemistry (IHC) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Enzyme Immunoassay (EIA) (7), Immunoprecipitation (IP) (5), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Dot Blot (Dot) (2)
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Epitopes
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pSer9 (10), pSer603 (5), pSer549 (4), pSer62 (2), pSer62/67 (2), C-Term (1), internal (1), pSer605 (1), pSer62, pSer67 (1)
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