Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1) antibody

Antigen: Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1)

Synonyms: VGAT, Viaat, R75019, CG8394, CG8394.2, DmelCG8394, vGAT, VIAAT, BGT1, Gat1, RNU28927, Vgat, Ci-vGAT, slc32a1, viaat, MGC68938, vgat, xVIAAT, MGC89195

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN361418

Additional Information

Alternative name: Vesicular GABA Amino Acid Transporter (VGAT)

Format: Affinity-purified

Description: The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005). Anti-Vesicular GABA Transporter (VGAT) Western blot of rat hippocampal lysate showing specific immunolabeling of the ~53k VGAT protein.

Specificity: Specific for the ~53k VGAT protein.

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Purification: Prepared from rabbit serum by affinity purification on a column made with the peptide used as antigen.

Storage: Store at -20 °C, stable for 1 year

Restrictions: For Research Use only

Images

Western blots of rat hippocampal lysate showing specific immunolabeling of the ~53k VGAT protein.

Publications

Publications: Korn, Koppel, Li et al.: "Astrocyte-secreted factors modulate the developmental distribution of inhibitory synapses in nucleus laminaris of the avian auditory brainstem." in: The Journal of comparative neurology, 2011 (PubMed).