Dopamine Transporter (DAT) (C-Term) antibody

Antigen: Dopamine Transporter (DAT)

Synonyms: dat, Dat, GB15426, DAT, Dat1, DAT1, dDAT, fmn, DmelCG8380, CG8380

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Macaque

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN361429

Additional Information

Alternative name: Dopamine Transporter, C-Terminus

Format: Affinity-purified

Description: The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson?s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996). Anti-Dopamine Transporter Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.

Specificity: Specific for the ~88k DAT protein in Western blots. Cross-reaction with rat observed.

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 IHC: (frozen sections, formaldehyde fixed tissue, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.

Purification: Prepared from rabbit serum by affinity purification using a SulfoLink® column matrix to which the peptide immunogen was coupled.

Storage: Store at -20 °C, stable for 1 year

Restrictions: For Research Use only

Images

Western blots of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.