Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3) antibody

Antigen: Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3)

Synonyms: GLUH1, GLUR1, GLURA, HBGR1, MGC133252, GLUR2, GLURB, HBGR2, GluR-K2, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, GluA2, Glur2, GluR-B, Glur-2, GluR2, gluR-B, gluR-A

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN361454

Additional Information

Alternative name: GluR2/3

Format: Affinity-purified

Description: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002). Anti-GluR2/3 Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein.

Specificity: Specific for the ~100k GluR2/3 protein.

Synonyms: GLUH1, GLUR1, GLURA, HBGR1, MGC133252, GLUR2, GLURB, HBGR2, GluR-K2, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, GluA2, Glur2, GluR-B, Glur-2, GluR2, gluR-B, gluR-A

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Purification: Prepared from rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as antigen.

Storage: Store at -20 °C, stable for 1 year

Restrictions: For Research Use only

Images

Western blots of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein.