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Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibody

Antigen

Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6)

Synonyms TRP6, FSGS2, FLJ11098, FLJ14863, Trrp6, mtrp6, AV025995, LLHWJM002, LLHWJM003, LLHWJM004, TRPC6, trp6, trpc6, bZ1P14.9, si:rp71-1p14.9, Trpc6
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Mouse (Murine), Rabbit

Application
Alternatives ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
1 reference available
Catalog no. ABIN361534
Quantity 25 ug  (0.25 mg/ml)
Price 865.64 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name Trpc6
Gene ID 22068
Immunogen Partial peptide of Mouse Trpc6 (C-terminal)
Format Affinity-purified
Description Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by aphosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated bydiacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellularcalcium store depletion Tissue specificity: Lung and brain. Post-translational modification: N-glycosylated Sequence similarities: Belongs to the transient receptor family. STrpC subfamily. Contains 3 ANK repeats.

Application Details

Application Notes ELISA: 1.0ug/ml. IHC: 5-10ug/ml. ICC: 1-5ug/ml
Concentration 0.25 mg/ml
Purification Antigen Affinity
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20 degrees Celsius
Research Area Channels
Restrictions For Research Use only

Publications

Publications Inoue, Okada, Onoue et al.: "The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel." in: Circulation research, Vol. 88, Issue 3, pp. 325-32, 2001 (PubMed).

Alternatives

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6)", type "Antibodies"
Hosts Rabbit (50), Goat (6), Mouse (3), Sheep (3), Guinea Pig (1)
Reactivities Human (42), Mouse (Murine) (36), Rat (Rattus) (31), Cow (Bovine) (18), Dog (Canine) (18), Guinea Pig (18), Horse (Equine) (16), Pig (Porcine) (16), Rabbit (15), Zebrafish (Danio rerio) (3)
Applications Western Blotting (WB) (41), Flow Cytometry (FACS) (20), Immunofluorescence (IF) (19), Immunohistochemistry (IHC) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Enzyme Immunoassay (EIA) (7), ELISA (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (7), 4th cytoplasmic loop (5), 4th cytoplasmic domain (3), N-Term (3), 1st cytoplasmic loop (1), 4th cytoplasmic loop pS814 (1)