Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) antibody

Details for Product No. ABIN361542, Supplier: Log in to see
Antigen
  • CD23
  • Fcer2a
  • BLAST-2
  • CD23A
  • CLEC4J
  • FCE2
  • IGEBF
  • Fce2
  • Fcer2
  • Ly-42
  • Fc fragment of IgE, low affinity II, receptor for (CD23)
  • Fc receptor, IgE, low affinity II, alpha polypeptide
  • Fcer2
  • FCER2
  • Fcer2a
Alternatives
anti-Human Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Mouse (Murine), Human
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28
Host
Mouse
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137
97
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
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58
25
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1
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Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
407
115
91
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59
20
13
7
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2
1
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Options
Supplier
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Immunogen Mouse Fcalpha/muR expressing cell line
Clone TX61
Isotype IgG1 kappa
Purification ProteinG Affinity Purified
Alternative Name Fcalpha/muR (FCER2 Antibody Abstract)
Background Function: Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates theirendocytosis. May function in the immune response to microbes mediated by IgA and IgM Subcellular location: Cell membrane, Single-pass type I membrane protein Tissue specificity: Expressed in several tissues including thymus, spleen, liver, kidney, small and large intestine, testis and placenta.Expressed by oligodendrocytes, B cells and macrophages but not granulocytes, T cells or NK cells (at protein level) Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Gene ID 64435
Research Area Immunology
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes IP: 5-10ug/ml. FACS: 0.5-1ug/ml. IF: 5.0-10ug/ml
Restrictions For Research Use only
Concentration 0.25 mg/ml
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Preservative ProClin
Storage -20 °C
Background publications Cho, Usui, Honda, Tahara-Hanaoka, Shibuya, Shibuya: "Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR." in: Biochemical and biophysical research communications, Vol. 345, Issue 1, pp. 474-8, 2006 (PubMed).

Shibuya, Sakamoto, Shimizu, Shibuya, Osawa, Hiroyama, Eyre, Sutherland, Endo, Fujita, Miyabayashi, Sakano, Tsuji, Nakayama, Phillips, Lanier, Nakauchi: "Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes." in: Nature immunology, Vol. 1, Issue 5, pp. 441-6, 2001 (PubMed).

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