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Fc Receptor, IgA, IgM, High Affinity (FCAMR) antibody

Antigen

Fc Receptor, IgA, IgM, High Affinity (FCAMR)
Synonyms MGC129330, MGC129331, FCA/MR, FKSG87, FCAMR, DKFZp469K1129
Clonality Monoclonal (TX61)
Host
Alternatives

Mouse
Reactivity
Alternatives

Mouse (Murine), Human
Application
Alternatives Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)
2 references available
Catalog no. ABIN361542
Quantity 50 ug  (0.25 mg/ml)
Price 942.65 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

anti-Fc Receptor, IgA, IgM, High Affinity (FCAMR) antibody

anti-Fc Receptor, IgA, IgM, High Affinity (FCAMR) antibody (2)

anti-Fc Receptor, IgA, IgM, High Affinity (FCAMR) antibody (3)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name Fcalpha/muR
Gene ID 64435
Immunogen Mouse Fcalpha/muR expressing cell line
Format Affinity-purified
Isotype IgG1-kappa
Clone TX61
Description Function: Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates theirendocytosis. May function in the immune response to microbes mediated by IgA and IgM Subcellular location: Cell membrane, Single-pass type I membrane protein Tissue specificity: Expressed in several tissues including thymus, spleen, liver, kidney, small and large intestine, testis and placenta.Expressed by oligodendrocytes, B cells and macrophages but not granulocytes, T cells or NK cells (at protein level) Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Application Details
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Application Notes IP: 5-10ug/ml. FACS: 0.5-1ug/ml. IF: 5.0-10ug/ml
Concentration 0.25 mg/ml
Purification ProteinG Affinity Purified
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20 degrees Celsius
Research Area Immunology
Restrictions For Research Use only

Publications
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Publications Shibuya, Sakamoto, Shimizu et al.: "Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes." in: Nature immunology, Vol. 1, Issue 5, pp. 441-6, 2001 (PubMed).

Cho, Usui, Honda et al.: "Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR." in: Biochemical and biophysical research communications, Vol. 345, Issue 1, pp. 474-8, 2006 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Fc Receptor, IgA, IgM, High Affinity (FCAMR)", type "Antibodies"
Hosts Mouse (1)
Reactivities Mouse (Murine) (1)
Applications Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1), Neutralization (Neut) (1)