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Sphingosine-1-Phosphate Receptor 4 (S1PR4) antibody

Antigen

Sphingosine-1-Phosphate Receptor 4 (S1PR4)

Synonyms EDG3, LPB3, S1P3, EDG-3, FLJ37523, FLJ93220, MGC71696, EDG6, LPC1, S1P4, SLP4, Edg6, lpC1, MGC129298, S1PR4, edg6
Clonality Polyclonal
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
3 references available
Catalog no. ABIN361550
Quantity 50 ug  (1 mg/ml)
Price 627.13 $   Plus shipping costs $45.00
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Availability Will be delivered in 9 to 11 Business Days

Additional Information

Alternative name EDG6
Gene ID 8698
Immunogen Recombinant protein of full length Human EDG6
Format Affinity-purified
Description Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diversephysiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level ofexpression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bonemarrow, and appendix as well as in fetal liver, thymus, and lung Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details

Application Notes WB: 1ug/ml.
Concentration 1 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications

Gräler, Bernhardt, Lipp: "EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue." in: Genomics, Vol. 53, Issue 2, pp. 164-9, 1998 (PubMed).

Yamazaki, Kon, Sato et al.: "Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 583-9, 2000 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Alternatives

Alternatives for antigen "Sphingosine-1-Phosphate Receptor 4 (S1PR4)", type "Antibodies"
Hosts Rabbit (43), Mouse (6)
Reactivities Human (45), Mouse (Murine) (22), Horse (Equine) (18), Rat (Rattus) (18)
Applications Immunofluorescence (IF) (24), Western Blotting (WB) (24), Flow Cytometry (FACS) (18), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) pro (IHC (p)+) (3), Immunoelectron Microscopy (IEM) (1)
Conjugates FITC (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (8), N-Term (3), Cytoplasmic Domain (2), Internal Region (1)