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Sphingosine-1-Phosphate Receptor 4 (S1PR4) antibody

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Synonyms EDG6, edg6, LPC1, S1P4, SLP4, Edg6, Lpc1, S1p4
(102), (28), (17)
(94), (8)
(5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(57), (35), (20), (19), (11), (8), (3), (2), (1)
Pubmed 3 references available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
Immunogen Recombinant protein of full length Human EDG6
Purification Protein A purified
Alternative Name EDG6 (S1PR4 Antibody Abstract)
Background Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diversephysiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level ofexpression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bonemarrow, and appendix as well as in fetal liver, thymus, and lung Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Gene ID 8698
Research Area Signaling
Application Notes WB: 1ug/ml.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Yamazaki, Kon, Sato et al.: "Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 583-9, 2000 (PubMed).

Gräler, Bernhardt, Lipp: "EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue." in: Genomics, Vol. 53, Issue 2, pp. 164-9, 1998 (PubMed).

Catalog No. ABIN361550
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