Oxoeicosanoid Receptor 1 (OXER1) antibody

Antigen: Oxoeicosanoid Receptor 1 (OXER1)

Synonyms: GPCR, GPR170, TG1019

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN361552

Additional Information

Alternative name: OXER1

Gene ID: 165140

Immunogen: Recombinant protein of full length Human OXER1

Format: Affinity-purified

Description: Function: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE),5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoicacid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), familiesof heteromeric G proteins Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, andspleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details

Application Notes: WB: 1ug/ml.

Concentration: 1 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Signaling

Restrictions: For Research Use only

Images

OXER1 transfected 293T cell lysate 0 0

OXER1 transfected 293T cell lysate 0 0

Publications

Publications: Takeda, Kadowaki, Haga et al.: "Identification of G protein-coupled receptor genes from the human genome sequence." in: FEBS letters, Vol. 520, Issue 1-3, pp. 97-101, 2002 (PubMed).

Hosoi, Koguchi, Sugikawa et al.: "Identification of a novel human eicosanoid receptor coupled to G(i/o)." in: The Journal of biological chemistry, Vol. 277, Issue 35, pp. 31459-65, 2002 (PubMed).

Jones, Holden, Tenaillon et al.: "Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils." in: Molecular pharmacology, Vol. 63, Issue 3, pp. 471-7, 2003 (PubMed).