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Chloride Intracellular Channel 2 (CLIC2) antibody

Antigen

Chloride Intracellular Channel 2 (CLIC2)

Synonyms CLIC2b, XAP121, MGC108828, CLIC2, zgc:92762, MGC148419
Clonality Polyclonal
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB)
3 references available
Catalog no. ABIN361555
Quantity 50 ug  (1 mg/ml)
Price 627.13 $   Plus shipping costs $45.00
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Additional Information

Alternative name CLIC2
Gene ID 1193
Immunogen Recombinant protein of full length Human CLIC2
Format Affinity-purified
Description Function: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems tobe redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx Subcellular location: Cytoplasm. Membrane, Single-pass membrane protein Probable. Note: Exists both as soluble cytoplasmic protein andas membrane protein with probably a single transmembrane domain Tissue specificity: Detected in adult brain, heart, liver, lung, spleen, stomach and testis. Expressed in fetal liver and adult skeletal muscle Sequence similarities: Belongs to the chloride channel CLIC family. Contains 1 GST C-terminal domain.

Application Details

Application Notes WB: 1ug/ml.
Concentration 1 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Transporters
Restrictions For Research Use only

Publications

Heiss, Poustka: "Genomic structure of a novel chloride channel gene, CLIC2, in Xq28." in: Genomics, Vol. 45, Issue 1, pp. 224-8, 1997 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Alternatives

Alternatives for antigen "Chloride Intracellular Channel 2 (CLIC2)", type "Antibodies"
Hosts Rabbit (8), Mouse (1)
Reactivities Human (7), Rat (Rattus) (3), Cow (Bovine) (2), Rabbit (2), Chicken (1), Dog (Canine) (1), Mouse (Murine) (1)
Applications Western Blotting (WB) (9), ELISA (1), Immunocytochemistry (ICC) (1)
Epitopes AA 1-247 (1), C-Term (1), Internal Region (1)