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Chloride Intracellular Channel 2 (CLIC2) antibody

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Synonyms zgc:92762, CLIC2, CLIC2b, MRXS32, XAP121
(35), (18), (15), (3), (2), (2), (1)
(27), (8)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(24), (11), (7), (3), (1), (1), (1)
Pubmed 3 references available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
Immunogen Recombinant protein of full length Human CLIC2
Purification Protein A purified
Alternative Name CLIC2 (CLIC2 Antibody Abstract)
Background Function: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems tobe redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx Subcellular location: Cytoplasm. Membrane, Single-pass membrane protein Probable. Note: Exists both as soluble cytoplasmic protein andas membrane protein with probably a single transmembrane domain Tissue specificity: Detected in adult brain, heart, liver, lung, spleen, stomach and testis. Expressed in fetal liver and adult skeletal muscle Sequence similarities: Belongs to the chloride channel CLIC family. Contains 1 GST C-terminal domain.
Gene ID 1193
Research Area Transporters
Application Notes WB: 1ug/ml.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Heiss, Poustka: "Genomic structure of a novel chloride channel gene, CLIC2, in Xq28." in: Genomics, Vol. 45, Issue 1, pp. 224-8, 1997 (PubMed).

Catalog No. ABIN361555
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