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RGS7 antibody (regulates activation and deactivation kinetics of G-protein coupled inward rectifier K+ channel)

Details for Product anti-RGS7 Antibody No. ABIN361562, Supplier: Log in to see
Antigen
  • zgc:92793
  • RGS7
Reactivity
Human, Rat (Rattus)
45
14
12
2
Host
Mouse
41
3
2
Clonality
Polyclonal
Conjugate
This RGS7 antibody is un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Western Blotting (WB)
42
24
20
3
2
2
1
1
Supplier
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Immunogen Recombinant protein of full length Human RGS7
Purification Protein A purified
Alternative Name RGS7
Background Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis.May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.
Gene ID 6000
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).

Kim, Arnould, Sellin et al.: "Interaction between RGS7 and polycystin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6371-6, 1999 (PubMed).

Koelle, Horvitz: "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins." in: Cell, Vol. 84, Issue 1, pp. 115-25, 1996 (PubMed).