Regulator of G-Protein Signaling 7 (RGS7) antibody

Details for Product No. ABIN361562
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Antigen
Synonyms zgc:92793, RGS7
Reactivity
Human, Rat (Rattus)
(20), (10), (10), (1)
Host
Mouse
(19), (2), (1)
Clonality
Polyclonal
Application
Western Blotting (WB), Flow Cytometry (FACS)
(20), (10), (4), (2), (2), (2), (1)
Pubmed 3 references available
Catalog no. ABIN361562
Quantity 50 µg
Price
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Immunogen Recombinant protein of full length Human RGS7
Purification Protein A purified
Alternative Name RGS7
Background Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis.May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.
Gene ID 6000
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
General Koelle, Horvitz: "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins." in: Cell, Vol. 84, Issue 1, pp. 115-25, 1996 (PubMed).

Kim, Arnould, Sellin et al.: "Interaction between RGS7 and polycystin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6371-6, 1999 (PubMed).

Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).

Hosts (19), (2), (1)
Reactivities (20), (10), (10), (1)
Applications (20), (10), (4), (2), (2), (2), (1)
Epitopes (3), (3), (2), (2), (2), (1), (1)
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