rho GTPase Activating Protein 4 (ARHGAP4) antibody

Antigen: rho GTPase Activating Protein 4 (ARHGAP4)

Synonyms: C1, RGC1, p115, RhoGAP4, KIAA0131

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Flow Cytometry (FACS)

Catalog no.: ABIN361566

Additional Information

Alternative name: ARHGAP4

Gene ID: 393

Immunogen: Recombinant protein of full length Human ARHGAP4

Format: Affinity-purified

Description: Function: Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells Subcellular location: Cytoplasm. Note: Just below the plasma membrane Tissue specificity: Predominantly in hematopoietic cells (spleen, thymus and leukocytes), low levels in placenta, lung and various fetaltissues Sequence similarities: Contains 1 FCH domain. Contains 1 Rho-GAP domain. Contains 1 SH3 domain.

Application Details

Application Notes: WB: 1ug/ml. FACS: 1ug/ml

Concentration: 1 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Signaling

Restrictions: For Research Use only

Images

human placenta tissue lysate ARHGAP4 transfected 293T cell lysate

human placenta tissue lysate ARHGAP4 transfected 293T cell lysate

ARHGAP4 expressing 293 cells. Negative control Transfectant

Publications

Publications: Tribioli, Mancini, Plassart et al.: "Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae." in: Human molecular genetics, Vol. 3, Issue 7, pp. 1061-7, 1995 (PubMed).

Tribioli, Droetto, Bione et al.: "An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 2, pp. 695-9, 1996 (PubMed).

Nagase, Seki, Tanaka et al.: "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 2, Issue 4, pp. 167-74, 199-210, 1996 (PubMed).