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RGS6 antibody (Regulator of G-Protein Signaling 6)

Details for Product anti-RGS6 Antibody No. ABIN361567, Supplier: Log in to see
Antigen
  • RGS6
  • DKFZp459O0734
  • GAP
  • hm:zeh0300
  • si:ch211-268e23.2
Reactivity
Human, Rat (Rattus)
20
9
6
4
1
1
1
Host
Mouse
13
4
3
1
Clonality
Polyclonal
Application
Flow Cytometry (FACS), Western Blotting (WB)
21
7
7
2
2
1
1
1
1
Supplier
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Immunogen Recombinant protein of full length Human RGS6
Purification Protein A purified
Alternative Name RGS6 (RGS6 Antibody Abstract)
Background Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer Subcellular location: Cytoplasm. Membrane, Peripheral membrane protein Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.
Gene ID 9628
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Chatterjee, Liu, Fisher: "Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30261-71, 2003 (PubMed).

Posner, Gilman, Harris: "Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways." in: The Journal of biological chemistry, Vol. 274, Issue 43, pp. 31087-93, 1999 (PubMed).

Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).