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Regulator of G-Protein Signaling 6 (RGS6) antibody

Details for Product No. ABIN361567
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Antigen
Synonyms RGS6, DKFZp459O0734, GAP, hm:zeh0300, si:ch211-268e23.2
Reactivity
Human, Rat (Rattus)
(13), (4), (2), (1), (1), (1), (1)
Host
Mouse
(8), (3), (2), (1), (1)
Clonality
Polyclonal
Application
Western Blotting (WB), Flow Cytometry (FACS)
(15), (4), (2), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 50 µg
Shipping to United States (Change)
Availability Will be delivered in 9 to 11 Business Days
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Catalog No. ABIN361567
627.13 $
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Immunogen Recombinant protein of full length Human RGS6
Purification Protein A purified
Alternative Name RGS6
Background Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer Subcellular location: Cytoplasm. Membrane, Peripheral membrane protein Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.
Gene ID 9628
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
General Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).

Posner, Gilman, Harris: "Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways." in: The Journal of biological chemistry, Vol. 274, Issue 43, pp. 31087-93, 1999 (PubMed).

Chatterjee, Liu, Fisher: "Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30261-71, 2003 (PubMed).

Validation Images
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