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Regulator of G-Protein Signalling 6 (RGS6) antibody

Antigen

Regulator of G-Protein Signalling 6 (RGS6)
Synonyms GAP, FLJ43552, MGC142132, DKFZp313G1241, RGS6, hm:zeh0300, si:ch211-268e23.2
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Rat (Rattus)
Application
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
3 references available
Catalog no. ABIN361567
Quantity 50 ug  (0.5 mg/ml)
Price 619.19 $   Plus shipping costs $35.00
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anti-Regulator of G-Protein Signalling 6 (RGS6) antibody

anti-Regulator of G-Protein Signalling 6 (RGS6) antibody (2)

anti-Regulator of G-Protein Signalling 6 (RGS6) antibody (3)

Additional Information
Application Details Publications Images Alternatives Secondary Antibodies back to top

Alternative name RGS6
Gene ID 9628
Immunogen Recombinant protein of full length Human RGS6
Format Affinity-purified
Description Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactiveGDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer Subcellular location: Cytoplasm. Membrane, Peripheral membrane protein Sequence similarities: Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain.

Application Details
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Application Notes WB: 1ug/ml. FACS: 1ug/ml
Concentration 0.5 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications
Application Details Images Alternatives Secondary Antibodies back to top

Publications Snow, Betts, Mangion et al.: "Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 11, pp. 6489-94, 1999 (PubMed).

Posner, Gilman, Harris: "Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways." in: The Journal of biological chemistry, Vol. 274, Issue 43, pp. 31087-93, 1999 (PubMed).

Chatterjee, Liu, Fisher: "Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30261-71, 2003 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies back to top

Alternatives for antigen "Regulator of G-Protein Signalling 6 (RGS6)", type "Antibodies"
Hosts Rabbit (7), Mouse (3), Chicken (1), Goat (1)
Reactivities Human (10), Mouse (Murine) (2), Chicken (1), Rat (Rattus) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (11), Immunohistochemistry (IHC) (4), ELISA (2), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Flow Cytometry (FACS) (2), Immunocytochemistry (ICC) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)