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Growth Factor Receptor-Bound Protein 7 (GRB7) antibody
| Antigen | Growth Factor Receptor-Bound Protein 7 (GRB7) |
| Synonyms | KIAA4028, MGC78181, mKIAA4028, MGC93307, GRB7, MGC138032 |
| Clonality | Polyclonal |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
|
 |
3 references available |
| Catalog no. | ABIN361568 |
| Quantity | 50 ug (0.26 mg/ml) |
| Price | 619.19 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | GRB7 |
| Gene ID | 2886 |
| Immunogen | Recombinant protein of full length Human GRB7 |
| Format | Affinity-purified |
| Description | Function: Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediatedby the SH2 domain. Also binds to ERBB2 Sequence similarities: Belongs to the GRB7/10/14 family. Contains 1 PH domain. Contains 1 Ras-associating domain. Contains 1 SH2domain. |
Application Details
| Application Notes | WB: 1ug/ml. FACS: 1ug/ml |
| Concentration | 0.26 mg/ml |
| Purification | Protein A purified |
| Buffer | PBS, pH 7.2 |
| Storage | Store below -20 degrees Celsius |
| Research Area | Signaling |
| Restrictions | For Research Use only |
Images
| human stomach tissue lysate GRB7 transfected 293T cell lysate human stomach tissue lysate GRB7 transfected 293T cell lysate GRB7 expressing 293 cells. Negative control Transfectant |
Publications
| Publications |
Tanaka, Mori, Akiyoshi et al.: "Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma." in: Cancer research, Vol. 57, Issue 1, pp. 28-31, 1997 (PubMed).
Kishi, Sasaki, Akiyama et al.: "Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer." in: Biochemical and biophysical research communications, Vol. 232, Issue 1, pp. 5-9, 1997 (PubMed). Tanaka, Mori, Akiyoshi et al.: "A novel variant of human Grb7 is associated with invasive esophageal carcinoma." in: The Journal of clinical investigation, Vol. 102, Issue 4, pp. 821-7, 1998 (PubMed). |
Alternatives
Alternatives for antigen "Growth Factor Receptor-Bound Protein 7 (GRB7)", type "Antibodies"
| Hosts | Rabbit (4), Goat (3), Mouse (3) |
| Reactivities | Human (9) |
| Applications | Western Blotting (WB) (9), Enzyme Immunoassay (EIA) (4), ELISA (Detection) (3), Flow Cytometry (FACS) (2), ELISA (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1) |
| Epitopes | N-Term (2) |
