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Details for Product No. ABIN361571

Hemochromatosis (HFE) antibody

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Antigen
Synonyms HFE1, HH, HLA-H, MVCD7, TFQTL2, MR2
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN361571
Quantity 50 µg
Price
627.13 $   Plus shipping costs $45.00
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Availability Will be delivered in 9 to 11 Business Days
Immunogen Recombinant protein of full length Human HFE
Purification Protein A purified
Alternative Name HFE
Background Function: Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin Subcellular location: Membrane, Single-pass type I membrane protein Tissue specificity: In all tissues tested except brain Sequence similarities: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Gene ID 3077
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.44 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Feder, Gnirke, Thomas et al.: "A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis." in: Nature genetics, Vol. 13, Issue 4, pp. 399-408, 1996 (PubMed).

Ruddy, Kronmal, Lee et al.: "A 1.1-Mb transcript map of the hereditary hemochromatosis locus." in: Genome research, Vol. 7, Issue 5, pp. 441-56, 1997 (PubMed).

Albig, Drabent, Burmester et al.: "The haemochromatosis candidate gene HFE (HLA-H) of man and mouse is located in syntenic regions within the histone gene cluster." in: Journal of cellular biochemistry, Vol. 69, Issue 2, pp. 117-26, 1998 (PubMed).

Alternatives for antigen "Hemochromatosis (HFE)", type "Antibodies"
Hosts (36), (8)
Reactivities (42), (22), (20), (18), (17)
Applications (29), (16), (14), (10), (8), (4), (4), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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