Hemochromatosis (HFE) antibody

Details for Product No. ABIN361571
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Antigen
Synonyms HFE1, HH, HLA-H, MVCD7, TFQTL2, MR2
Reactivity
Human
(60), (21), (17), (1)
Host
Mouse
(50), (13)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(49), (22), (14), (14), (11), (10), (5), (3), (2), (1)
Pubmed 3 references available
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Recombinant protein of full length Human HFE
Purification Protein A purified
Alternative Name HFE (HFE Antibody Abstract)
Background Function: Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin Subcellular location: Membrane, Single-pass type I membrane protein Tissue specificity: In all tissues tested except brain Sequence similarities: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Gene ID 3077
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.44 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
General Albig, Drabent, Burmester et al.: "The haemochromatosis candidate gene HFE (HLA-H) of man and mouse is located in syntenic regions within the histone gene cluster." in: Journal of cellular biochemistry, Vol. 69, Issue 2, pp. 117-26, 1998 (PubMed).

Ruddy, Kronmal, Lee et al.: "A 1.1-Mb transcript map of the hereditary hemochromatosis locus." in: Genome research, Vol. 7, Issue 5, pp. 441-56, 1997 (PubMed).

Feder, Gnirke, Thomas et al.: "A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis." in: Nature genetics, Vol. 13, Issue 4, pp. 399-408, 1996 (PubMed).

Validation Images
Catalog No. ABIN361571
496.41 $
Plus shipping costs $45.00
Quantity
Price
50 μg
496.41 $

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