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Sphingosine-1-Phosphate Receptor 3 (S1PR3) antibody

Antigen

Sphingosine-1-Phosphate Receptor 3 (S1PR3)

Synonyms si:dkeyp-31e2.1, EDG3, LPB3, S1P3, EDG-3, FLJ37523, FLJ93220, MGC71696, EDG6, LPC1, S1P4, SLP4
Clonality Polyclonal
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
3 references available
Catalog no. ABIN361593
Quantity 50 ug  (0.5 mg/ml)
Price 619.19 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information

Alternative name EDG3
Gene ID 1903
Immunogen Recombinant protein of full length Human EDG3
Format Affinity-purified
Description Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diversephysiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-inducedcell proliferation and suppression of apoptosis Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details

Application Notes WB: 1ug/ml. FACS: 1ug/ml
Concentration 0.5 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications

Publications Yamaguchi, Tokuda, Hatase et al.: "Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9." in: Biochemical and biophysical research communications, Vol. 227, Issue 2, pp. 608-14, 1996 (PubMed).

An, Bleu, Huang et al.: "Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids." in: FEBS letters, Vol. 417, Issue 3, pp. 279-82, 1998 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Alternatives

Alternatives for antigen "Sphingosine-1-Phosphate Receptor 3 (S1PR3)", type "Antibodies"
Hosts Rabbit (34), Mouse (7)
Reactivities Human (41), Rat (Rattus) (17), Mouse (Murine) (14), Cow (Bovine) (7), Dog (Canine) (6), Horse (Equine) (6), Pig (Porcine) (6), Rabbit (4), Chicken (2)
Applications Western Blotting (WB) (21), Immunofluorescence (IF) (19), Flow Cytometry (FACS) (17), Enzyme Immunoassay (EIA) (7), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes C-Term (4), N-Term (3)