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Details for Product No. ABIN361594

Formyl Peptide Receptor 2 (FPR2) antibody

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Synonyms ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, E330010I07Rik, Fpr-rs2, Fprl1, ALX, Fpr-rs1, Fpr-s1, LXA4-R, Lxa4r, FPR2, FMLP-R-I
»Alternatives Human
»Alternatives Mouse
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN361594
Quantity 50 µg
627.13 $   Plus shipping costs $45.00
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Immunogen Recombinant protein of full length Human FPRL1
Purification Protein A purified
Alternative Name FPRL1
Background Function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to thereceptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium secondmessenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatorysignals such as LTB4 (leukotriene B4) Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Gene ID 2358
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Ye, Cavanagh, Quehenberger et al.: "Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor." in: Biochemical and biophysical research communications, Vol. 184, Issue 2, pp. 582-9, 1992 (PubMed).

Perez, Holmes, Kelly et al.: "Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils." in: Gene, Vol. 118, Issue 2, pp. 303-4, 1992 (PubMed).

Bao, Gerard, Eddy et al.: "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19." in: Genomics, Vol. 13, Issue 2, pp. 437-40, 1992 (PubMed).

Alternatives for antigen "Formyl Peptide Receptor 2 (FPR2)", type "Antibodies"
Hosts (30), (14), (10), (1)
Reactivities (53), (13), (12)
Applications (27), (19), (11), (10), (8), (5), (2), (2), (2), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)