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Formyl Peptide Receptor 2 (FPR2) antibody

Antigen

Formyl Peptide Receptor 2 (FPR2)
Synonyms ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, Fpr-rs2, MGC151443, E330010I07Rik, FPR2, Fprl1, ALX, Lxa4r, LXA4-R, Fpr-rs1, FMLP-R-I
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
3 references available
Catalog no. ABIN361594
Quantity 50 ug  (1 mg/ml)
Price 627.13 $   Plus shipping costs $45.00
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anti-Formyl Peptide Receptor 2 (FPR2) antibody

anti-Formyl Peptide Receptor 2 (FPR2) antibody (2)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name FPRL1
Gene ID 2358
Immunogen Recombinant protein of full length Human FPRL1
Format Affinity-purified
Description Function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to thereceptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium secondmessenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatorysignals such as LTB4 (leukotriene B4) Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details
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Application Notes WB: 1ug/ml. FACS: 1ug/ml
Concentration 1 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Ye, Cavanagh, Quehenberger et al.: "Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor." in: Biochemical and biophysical research communications, Vol. 184, Issue 2, pp. 582-9, 1992 (PubMed).

Perez, Holmes, Kelly et al.: "Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils." in: Gene, Vol. 118, Issue 2, pp. 303-4, 1992 (PubMed).

Bao, Gerard, Eddy et al.: "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19." in: Genomics, Vol. 13, Issue 2, pp. 437-40, 1992 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Formyl Peptide Receptor 2 (FPR2)", type "Antibodies"
Hosts Rabbit (34), Mouse (11), Goat (6)
Reactivities Human (47), Mouse (Murine) (19), Rat (Rattus) (19)
Applications Immunofluorescence (IF) (24), Western Blotting (WB) (18), ELISA (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Flow Cytometry (FACS) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Enzyme Immunoassay (EIA) (2), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (5), AA 181-192 (4), AA 13-26 (3), AA 328-339 (3), C-Term 2nd Extracellular Loop (2), Center (2), Extracellular Domain (1), Internal Region (1), Internal Region,AA 127-153 (1), N-Term (1)