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anti-formyl peptide receptor 2 antibody

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Image for anti-formyl peptide receptor 2 antibody
Antigen: Formyl peptide receptor 2
Clonality: Polyclonal
Application: Western Blotting (WB), Flow Cytometry (FACS)
Reactivity: Human
Host: Mouse
3 references available 3 references available
Quantity: 50 ug (1 mg/ml)
Price: 589,42 $   (Plus shipping costs and VAT, Invoice in EUR)
Order number: ABIN361594
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Additional Information  » anti-formyl peptide receptor 2 antibody

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Antigen Formyl peptide receptor 2
Gene ID 2358
Immunogen Recombinant protein of full length Human FPRL1
Reactivity Human
Host Mouse
Clonality Polyclonal
Format Affinitiy-purified
Description Function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to thereceptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium secondmessenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatorysignals such as LTB4 (leukotriene B4) Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details  » anti-formyl peptide receptor 2 antibody

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Application Western Blotting (WB), Flow Cytometry (FACS)
» Click here to view 7 available protocols!
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Concentration 1 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications  » anti-formyl peptide receptor 2 antibody

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Publications Ye, Cavanagh, Quehenberger et al.: "Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor." In: Biochemical and biophysical research communications, Vol. 184, Issue 2, pp. 582-9, 1992 (PubMed)

Perez, Holmes, Kelly et al.: "Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils." In: Gene, Vol. 118, Issue 2, pp. 303-4, 1992 (PubMed)

Bao, Gerard, Eddy et al.: "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19." In: Genomics, Vol. 13, Issue 2, pp. 437-40, 1992 (PubMed)