Duffy Blood Group, Chemokine Receptor (DARC) antibody

Details for Product No. ABIN361595
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms DARC, FY, ACKR1, CCBP1, CD234, Dfy, GPD, GpFy, WBCQ1, AA162249, Ackr1, ESTM35
Reactivity
Human
(64), (27), (23)
Host
Mouse
(63), (7), (6), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(54), (44), (25), (15), (15), (9), (9), (5), (4), (1), (1)
Pubmed 3 references available
Quantity 50 μg
Shipping to United States (Change)
Availability Will be delivered in 9 to 11 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN361595
627.13 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant protein of full length Human DARC
Purification Protein A purified
Alternative Name DARC
Background Function: Non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC. It is also the receptor for thehuman malaria parasites Plasmodium vivax and Plasmodium knowlesi Subcellular location: Membrane, Multi-pass membrane protein Tissue specificity: Found in adult kidney, adult spleen, bone marrow and fetal liver. In particular, it is expressed along postcapillary venulesthroughout the body, except in the adult liver. Erythroid cells and postcapillary venule endothelium are the principle tissues expressing duffy.Fy(-A-B) individuals do not express duffy in the bone marrow, however they do, in postcapillary venule endothelium Sequence similarities: Belongs to the G-protein coupled receptor Duffy family.
Gene ID 2532
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
General Tournamille, Colin, Cartron et al.: "Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals." in: Nature genetics, Vol. 10, Issue 2, pp. 224-8, 1995 (PubMed).

Iwamoto, Omi, Kajii et al.: "Genomic organization of the glycoprotein D gene: Duffy blood group Fya/Fyb alloantigen system is associated with a polymorphism at the 44-amino acid residue." in: Blood, Vol. 85, Issue 3, pp. 622-6, 1995 (PubMed).

Chaudhuri, Polyakova, Zbrzezna et al.: "Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 22, pp. 10793-7, 1993 (PubMed).

Validation Images
Did you look for something else?
back to top