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Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) antibody

Antigen

Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3)
Synonyms EP3, EP3e, EP3-I, EP3-II, EP3-IV, EP3-III, MGC27302, MGC141828, MGC141829, PTGER3
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
3 references available
Catalog no. ABIN361598
Quantity 50 ug  (0.5 mg/ml)
Price 619.19 $   Plus shipping costs $35.00
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anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) antibody

anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) antibody (2)

Additional Information
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Alternative name PTGER3
Gene ID 5733
Immunogen Recombinant protein of full length Human PTGER3
Format Affinity-purified
Description Function: Receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation ofneurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction inuterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to anelevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different secondmessenger systems Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Application Details
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Application Notes WB: 1ug/ml. FACS: 1ug/ml
Concentration 0.5 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Signaling
Restrictions For Research Use only

Publications
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Publications Schmid, Thierauch, Schleuning et al.: "Splice variants of the human EP3 receptor for prostaglandin E2." in: European journal of biochemistry / FEBS, Vol. 228, Issue 1, pp. 23-30, 1995 (PubMed).

Yang, Xia, Goetzl et al.: "Cloning and expression of the EP3-subtype of human receptors for prostaglandin E2." in: Biochemical and biophysical research communications, Vol. 198, Issue 3, pp. 999-1006, 1994 (PubMed).

Adam, Boie, Rushmore et al.: "Cloning and expression of three isoforms of the human EP3 prostanoid receptor." in: FEBS letters, Vol. 338, Issue 2, pp. 170-4, 1994 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies back to top

Alternatives for antigen "Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3)", type "Antibodies"
Hosts Rabbit (12), Goat (6), Mouse (5)
Reactivities Human (13), Rat (Rattus) (4), Cow (Bovine) (2), Mouse (Murine) (2), Dog (Canine) (1)
Applications Western Blotting (WB) (16), Enzyme Immunoassay (EIA) (5), ELISA (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), ELISA (Detection) (2), Flow Cytometry (FACS) (2), Immunoprecipitation (IP) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Epitopes C-Term (2), Isoform 1 2 3 (1)