Retinal Outer Segment Membrane Protein 1 (ROM1) antibody

Antigen: Retinal Outer Segment Membrane Protein 1 (ROM1)

Synonyms: ROM, RP7, ROSP1, TSPAN23, ROM1, MGC139433, MGC105717

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Flow Cytometry (FACS)

Catalog no.: ABIN361599

Additional Information

Alternative name: ROM1

Gene ID: 6094

Immunogen: Recombinant protein of full length Human ROM1

Format: Affinity-purified

Description: Function: May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance ofthe curvature of the rim. It is essential for disk morphogenesis Subcellular location: Membrane, Multi-pass membrane protein Tissue specificity: Retina (photoreceptor). In rim region of ROS (rod outer segment) disks Sequence similarities: Belongs to the PRPH2/ROM1 family.

Application Details

Application Notes: WB: 1ug/ml. FACS: 1ug/ml

Concentration: 0.5 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Restrictions: For Research Use only

Images

ROM1 transfected 293T cell lysate

ROM1 transfected 293T cell lysate

ROM1 expressing 293 cells 0

Publications

Publications: Bascom, Manara, Collins et al.: "Cloning of the cDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies." in: Neuron, Vol. 8, Issue 6, pp. 1171-84, 1992 (PubMed).

Bascom, Schappert, McInnes: "Cloning of the human and murine ROM1 genes: genomic organization and sequence conservation." in: Human molecular genetics, Vol. 2, Issue 4, pp. 385-91, 1993 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).