Signal Sequence Receptor, alpha (SSR1) antibody

Antigen: Signal Sequence Receptor, alpha (SSR1)

Synonyms: TRAPA, FLJ14232, FLJ22100, FLJ23034, FLJ78242, FLJ93042, DKFZp781N23103, SSR, AI159733, AI452176, 6330400D04, 2510001K09Rik, Ac2-238, cb758, SSR1, MGC140667, trapa, Ssr1, DKFZp459D2114

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Flow Cytometry (FACS)

Catalog no.: ABIN361600

Additional Information

Alternative name: SSR1

Gene ID: 6745

Immunogen: Recombinant protein of full length Human SSR1

Format: Affinity-purified

Description: Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention ofER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or mayfunction as a membrane-bound chaperone facilitating folding of translocated proteins Subcellular location: Endoplasmic reticulum membrane, Single-pass type I membrane protein Sequence similarities: Belongs to the TRAP-alpha family.

Application Details

Application Notes: WB: 1ug/ml. FACS: 1ug/ml

Concentration: 0.5 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Signaling

Restrictions: For Research Use only

Images

SSR1 transfected 293T cell lysate

SSR1 transfected 293T cell lysate

SSR1 expressing 293 cells 0

Publications

Publications: Hartmann, Prehn: "The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges." in: FEBS letters, Vol. 349, Issue 3, pp. 324-6, 1994 (PubMed).

Hirama, Miller, Koeffler: "Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation." in: FEBS letters, Vol. 455, Issue 3, pp. 223-7, 1999 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).