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G Protein-Coupled Receptor 77 (GPR77) antibody

Details for Product No. ABIN361605, Supplier: Log in to see
Antigen
  • C5L2
  • E030029A11Rik
  • GPF77
  • Gpr77
  • GPR77
Reactivity
Human
90
3
3
2
1
1
Host
Mouse
81
9
1
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
4
4
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Western Blotting (WB)
39
27
25
22
11
7
2
2
1
Supplier
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Immunogen Recombinant protein of full length Human GPR77
Purification Protein A purified
Alternative Name GPR77 (GPR77 Antibody Abstract)
Background Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives.Couples weakly to Gi-mediated signaling pathways Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Frontal cortex, hippocampus, hypothalamus, pons and liver Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Gene ID 27202
Research Area Signaling
Application Notes WB: 1ug/ml. FACS: 1ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004

Cain, Monk: "The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)." in: The Journal of biological chemistry, Vol. 277, Issue 9, pp. 7165-9, 2002

Lee, George, Cheng, Nguyen, Liu, Brown, Lynch, ODowd: "Identification of four novel human G protein-coupled receptors expressed in the brain." in: Brain research. Molecular brain research, Vol. 86, Issue 1-2, pp. 13-22, 2001