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G Protein-Coupled Receptor 77 (GPR77) antibody
| Antigen | G Protein-Coupled Receptor 77 (GPR77) |
| Synonyms | C5L2, E030029A11Rik, Gpr77, GPR77, GPF77 |
| Clonality | Polyclonal |
| Host |
Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Flow Cytometry (FACS)
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3 references available |
| Catalog no. | ABIN361605 |
| Quantity | 50 ug (0.5 mg/ml) |
| Price | 619.19 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | GPR77 |
| Gene ID | 27202 |
| Immunogen | Recombinant protein of full length Human GPR77 |
| Format | Affinity-purified |
| Description | Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives.Couples weakly to Gi-mediated signaling pathways Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Frontal cortex, hippocampus, hypothalamus, pons and liver Sequence similarities: Belongs to the G-protein coupled receptor 1 family. |
Application Details
| Application Notes | WB: 1ug/ml. FACS: 1ug/ml |
| Concentration | 0.5 mg/ml |
| Purification | Protein A purified |
| Buffer | PBS, pH 7.2 |
| Storage | Store below -20 degrees Celsius |
| Research Area | Signaling |
| Restrictions | For Research Use only |
Images
| GPR77 transfected 293T cell lysate. Negative control Transfectant GPR77 expressing 293 cells 0 0 |
Publications
| Publications |
Lee, George, Cheng et al.: "Identification of four novel human G protein-coupled receptors expressed in the brain." in: Brain research. Molecular brain research, Vol. 86, Issue 1-2, pp. 13-22, 2001 (PubMed).
Cain, Monk: "The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)." in: The Journal of biological chemistry, Vol. 277, Issue 9, pp. 7165-9, 2002 (PubMed). Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed). |
Alternatives
Alternatives for antigen "G Protein-Coupled Receptor 77 (GPR77)", type "Antibodies"
| Hosts | Rabbit (8), Mouse (2), Rat (1) |
| Reactivities | Human (9), Monkey (2), Chimpanzee (1), Cow (Bovine) (1), Mouse (Murine) (1) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Western Blotting (WB) (4), Flow Cytometry (FACS) (3), Immunofluorescence (IF) (2), ELISA (Detection) (1) |
| Epitopes | C-Term (1), N-Term (1) |




Alternatives