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G Protein-Coupled Receptor 77 (GPR77) antibody
| Antigen | G Protein-Coupled Receptor 77 (GPR77) |
| Synonyms | C5L2, E030029A11Rik, Gpr77, GPR77, GPF77 |
| Clonality | Polyclonal |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Flow Cytometry (FACS) |
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3 references available |
| Catalog no. | ABIN361605 |
| Quantity | 50 ug (0.5 mg/ml) |
| Price | 627.13 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 9 to 11 Business Days |
Additional Information
| Alternative name | GPR77 |
| Gene ID | 27202 |
| Immunogen | Recombinant protein of full length Human GPR77 |
| Format | Affinity-purified |
| Description | Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives.Couples weakly to Gi-mediated signaling pathways Subcellular location: Cell membrane, Multi-pass membrane protein Tissue specificity: Frontal cortex, hippocampus, hypothalamus, pons and liver Sequence similarities: Belongs to the G-protein coupled receptor 1 family. |
Application Details
| Application Notes | WB: 1ug/ml. FACS: 1ug/ml |
| Concentration | 0.5 mg/ml |
| Purification | Protein A purified |
| Buffer | PBS, pH 7.2 |
| Storage | Store below -20 degrees Celsius |
| Research Area | Signaling |
| Restrictions | For Research Use only |
Images
| GPR77 transfected 293T cell lysate. Negative control Transfectant GPR77 expressing 293 cells 0 0 |
Publications
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Lee, George, Cheng et al.: "Identification of four novel human G protein-coupled receptors expressed in the brain." in: Brain research. Molecular brain research, Vol. 86, Issue 1-2, pp. 13-22, 2001 (PubMed).
Cain, Monk: "The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)." in: The Journal of biological chemistry, Vol. 277, Issue 9, pp. 7165-9, 2002 (PubMed). Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed). |
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Alternatives
Alternatives for antigen "G Protein-Coupled Receptor 77 (GPR77)", type "Antibodies"
| Hosts | Rabbit (15), Mouse (1), Rat (1) |
| Reactivities | Human (15), Monkey (2), Chimpanzee (1), Cow (Bovine) (1), Mouse (Murine) (1) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Western Blotting (WB) (5), ELISA (3), Flow Cytometry (FACS) (2), Immunofluorescence (IF) (2), Dot Blot (DB) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Epitopes | C-Term (3), N-Term (2), AA 1-50 (1), C-Term,AA 297-325 (1), Extracellular Domain (1) |
