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ATP2C1 antibody (ATPase, Ca++ Transporting, Type 2C, Member 1)

Details for Product anti-ATP2C1 Antibody No. ABIN361612, Supplier: Log in to see
Antigen
  • 1700121J11Rik
  • ATP2C1
  • ATP2C1A
  • AW061228
  • BCPM
  • D930003G21Rik
  • HHD
  • hSPCA1
  • pmr1
  • PMR1
  • si:dkey-11p23.6
  • SPCA
  • Spca1
  • SPCA1
Reactivity
Human
85
30
23
12
7
2
1
1
1
1
Host
Mouse
65
20
Clonality
Polyclonal
Conjugate
This ATP2C1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
68
41
22
12
10
6
3
3
2
2
1
Supplier
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Supplier Product No.
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Immunogen Recombinant protein of full length Human ATP2C1
Purification Protein A purified
Alternative Name ATP2C1 (ATP2C1 Antibody Abstract)
Background Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium Subcellular location: Golgi apparatus membrane, Multi-pass membrane protein Tissue specificity: Found in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney Sequence similarities: Belongs to the cation transport ATPase (P-type) family.
Gene ID 27032
Research Area Enzymes
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Fairclough, Dode, Vanoevelen, Andersen, Missiaen, Raeymaekers, Wuytack, Hovnanian: "Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1)." in: The Journal of biological chemistry, Vol. 278, Issue 27, pp. 24721-30, 2003

Hu, Bonifas, Beech, Bench, Shigihara, Ogawa, Ikeda, Mauro, Epstein: "Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease." in: Nature genetics, Vol. 24, Issue 1, pp. 61-5, 2000

Sudbrak, Brown, Dobson-Stone, Carter, Ramser, White, Healy, Dissanayake, Larruegue, Perrussel, Lehrach, Munro, Strachan, Burge, Hovnanian, Monaco: "Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump." in: Human molecular genetics, Vol. 9, Issue 7, pp. 1131-40, 2000