anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1)

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Antigen
Synonyms aif, pdcd8, PDCD8, AIFM1, AIF, PCD8, CG7263, DmAIF, Dmel\\CG7263, GB16024, DDBDRAFT_0187853, DDBDRAFT_0191137, DDB_0187853, DDB_0191137, AIFsh2, Hq, Pdcd8, mAIF, Aif, zgc:91994, CMTX4, COWCK, COXPD6
Alternatives
Reactivity
Human
(191), (80), (71), (15), (14), (9), (8), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1)
Host
Mouse
(165), (29), (2), (2)
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
(5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunofluorescence (IF)
(162), (76), (47), (41), (27), (22), (19), (11), (9), (6), (4), (3), (2)
Pubmed 3 references available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
Immunogen Recombinant protein of full length Human PDCD8
Purification Protein A purified
Alternative Name PDCD8 (AIFM1 Antibody Abstract)
Background Function: Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. ExtramitochondrialAIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro). Binds to DNA in a sequence-independentmanner Subcellular location: Mitochondrion intermembrane space. Nucleus. Note: Translocated to the nucleus upon induction of apoptosis Sequence similarities: Belongs to the FAD-dependent oxidoreductase family.
Gene ID 9131
Research Area Enzymes
Pathways Apoptosis
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Susin, Lorenzo, Zamzami et al.: "Molecular characterization of mitochondrial apoptosis-inducing factor." in: Nature, Vol. 397, Issue 6718, pp. 441-6, 1999 (PubMed).

Catalog No. ABIN361613
$491.00
Plus shipping costs $45.00

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