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Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody

Antigen

Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Synonyms AIF, PDCD8, MGC111425, aif, pdcd8, AIFM1, PCD8, DmelCG7263, GB16024
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunofluorescence (IF)
3 references available
Catalog no. ABIN361613
Quantity 50 ug  (1 mg/ml)
Price 627.13 $   Plus shipping costs $45.00
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Availability Will be delivered in 9 to 11 Business Days

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody (2)

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody (3)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name PDCD8
Gene ID 9131
Immunogen Recombinant protein of full length Human PDCD8
Format Affinity-purified
Description Function: Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. ExtramitochondrialAIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro). Binds to DNA in a sequence-independentmanner Subcellular location: Mitochondrion intermembrane space. Nucleus. Note: Translocated to the nucleus upon induction of apoptosis Sequence similarities: Belongs to the FAD-dependent oxidoreductase family.

Application Details
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Application Notes WB: 1ug/ml. IF: 10ug/ml
Concentration 1 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Enzymes
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Susin, Lorenzo, Zamzami et al.: "Molecular characterization of mitochondrial apoptosis-inducing factor." in: Nature, Vol. 397, Issue 6718, pp. 441-6, 1999 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)", type "Antibodies"
Hosts Rabbit (85), Mouse (24), Goat (1)
Reactivities Human (101), Mouse (Murine) (61), Rat (Rattus) (60), Cow (Bovine) (38), Dog (Canine) (38), Chicken (37), Pig (Porcine) (36), Sheep (Ovine) (36), Monkey (3), Cat (Feline) (1)
Applications Western Blotting (WB) (79), Immunofluorescence (IF) (42), ELISA (38), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Immunohistochemistry (IHC) (20), Immunocytochemistry (ICC) (16), Immunoprecipitation (IP) (8), Flow Cytometry (FACS) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
Epitopes N-Term (47), AA 593-606 (8), C-Term (7), AA 517-531 (6), AA 109-122 (5), Internal Region (2), AA 151-169 (1), AA 151-180 (1), Middle Region (1), N-Term,AA 77-106 (1), internal (1)