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AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1)

Details for Product anti-AIFM1 Antibody No. ABIN361613, Supplier: Log in to see
Antigen
  • aif
  • Aif
  • AIF
  • AIFM1
  • AIFsh2
  • CG7263
  • CMTX4
  • COWCK
  • COXPD6
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • Hq
  • mAIF
  • PCD8
  • PDCD8
  • pdcd8
  • Pdcd8
  • zgc:91994
Alternatives
anti-Human AIFM1 antibody for Western Blotting
Reactivity
Human
174
68
64
15
9
8
5
5
4
3
2
1
1
1
1
1
1
Host
Mouse
161
16
2
2
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
155
74
46
36
26
18
11
10
8
6
4
3
2
Supplier
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Immunogen Recombinant protein of full length Human PDCD8
Purification Protein A purified
Alternative Name PDCD8 (AIFM1 Antibody Abstract)
Background Function: Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. ExtramitochondrialAIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro). Binds to DNA in a sequence-independentmanner Subcellular location: Mitochondrion intermembrane space. Nucleus. Note: Translocated to the nucleus upon induction of apoptosis Sequence similarities: Belongs to the FAD-dependent oxidoreductase family.
Gene ID 9131
Research Area Enzymes
Pathways Apoptosis
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003

Susin, Lorenzo, Zamzami, Marzo, Snow, Brothers, Mangion, Jacotot, Costantini, Loeffler, Larochette, Goodlett, Aebersold, Siderovski, Penninger, Kroemer: "Molecular characterization of mitochondrial apoptosis-inducing factor." in: Nature, Vol. 397, Issue 6718, pp. 441-6, 1999