A Kinase (PRKA) Anchor Protein 8 (AKAP8) antibody

Antigen: A Kinase (PRKA) Anchor Protein 8 (AKAP8)

Synonyms: AKAP95, DKFZp586B1222, AA673585, AU015639, 1200016A02Rik, Akap95, AKAP8, MGC165917, MGC108502

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN361614

Additional Information

Alternative name: AKAP8

Gene ID: 10270

Immunogen: Recombinant protein of full length Human AKAP8

Format: Affinity-purified

Description: Function: Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) Subcellular location: Nucleus matrix. Note: Associated with the nuclear matrix. Redistributed and detached from condensed chromatinduring mitosis Tissue specificity: Highly expressed in heart, liver, skeletal muscle, kidney and pancreas Sequence similarities: Belongs to the AKAP95 family.

Application Details

Application Notes: WB: 1ug/ml. IF: 10ug/ml

Concentration: 1 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Signaling

Restrictions: For Research Use only

Images

AKAP8 transfected 293T cell lysate

AKAP8 transfected 293T cell lysate

HeLa cell 0

Publications

Publications: Eide, Coghlan, Orstavik et al.: "Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95." in: Experimental cell research, Vol. 238, Issue 2, pp. 305-16, 1998 (PubMed).

Grimwood, Gordon, Olsen et al.: "The DNA sequence and biology of human chromosome 19." in: Nature, Vol. 428, Issue 6982, pp. 529-35, 2004 (PubMed).

Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).