ARNT antibody (Aryl Hydrocarbon Receptor Nuclear Translocator)

Details for Product anti-ARNT Antibody No. ABIN361618, Supplier: Log in to see
Antigen
  • ARNT
  • zgc:136664
  • arnt1
  • hif1b
  • tango
  • xArnt
  • hif1beta
  • hif-1beta
  • HIF-1-beta
  • HIF-1beta
  • HIF1-beta
  • HIF1B
  • HIF1BETA
  • TANGO
  • bHLHe2
  • D3Ertd557e
  • Drnt
  • ESTM42
  • Hif1b
  • W08714
  • mKIAA4051
  • Arnt1
  • aryl hydrocarbon receptor nuclear translocator
  • Arnt
  • ARNT
  • arnt
  • Arnt
  • AHA-1
Alternatives
anti-Human ARNT antibody for Immunofluorescence
Reactivity
Human
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Host
Mouse
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Clonality
Polyclonal
Conjugate
This ARNT antibody is un-conjugated
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Application
Immunofluorescence (IF), Western Blotting (WB)
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Options
Supplier
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Supplier Product No.
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Immunogen Recombinant protein of full length Human ARNT
Purification Protein A purified
Alternative Name ARNT (ARNT Antibody Abstract)
Background Function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from thecytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAHprocarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia Subcellular location: Nucleus Sequence similarities: Contains 1 basic helix-loop-helix(bHLH) domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2PAS (PER-ARNT-SIM) domains.
Gene ID 405
Research Area Transporters
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, 2008 (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Hoffman, Reyes, Chu, Sander, Conley, Brooks, Hankinson: "Cloning of a factor required for activity of the Ah (dioxin) receptor." in: Science (New York, N.Y.), Vol. 252, Issue 5008, pp. 954-8, 1991 (PubMed).

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