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ARNT antibody (Aryl Hydrocarbon Receptor Nuclear Translocator)

Details for Product anti-ARNT Antibody No. ABIN361618, Supplier: Log in to see
Antigen
  • ARNT
  • arnt1
  • Arnt1
  • bHLHe2
  • D3Ertd557e
  • Drnt
  • ESTM42
  • HIF-1-beta
  • HIF-1beta
  • hif-1beta
  • HIF1-beta
  • Hif1b
  • HIF1B
  • hif1b
  • HIF1BETA
  • hif1beta
  • mKIAA4051
  • tango
  • TANGO
  • W08714
  • xArnt
  • zgc:136664
Reactivity
Human
152
61
55
24
22
22
15
3
2
1
Host
Mouse
76
62
20
Clonality
Polyclonal
Conjugate
This ARNT antibody is un-conjugated
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
130
52
50
39
31
25
15
12
10
7
4
3
3
2
1
1
Supplier
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Immunogen Recombinant protein of full length Human ARNT
Purification Protein A purified
Alternative Name ARNT (ARNT Antibody Abstract)
Background Function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from thecytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAHprocarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia Subcellular location: Nucleus Sequence similarities: Contains 1 basic helix-loop-helix(bHLH) domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2PAS (PER-ARNT-SIM) domains.
Gene ID 405
Research Area Transporters
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
Background publications Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, 2008 (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Hoffman, Reyes, Chu, Sander, Conley, Brooks, Hankinson: "Cloning of a factor required for activity of the Ah (dioxin) receptor." in: Science (New York, N.Y.), Vol. 252, Issue 5008, pp. 954-8, 1991 (PubMed).