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UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) antibody

Antigen

UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A)
Synonyms UPF3, HUPF3A, RENT3A, MGC151365, 2600001C03Rik, 4930546M19Rik, UPF3A, si:dkey-21o13.6
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Western Blotting (WB), Immunofluorescence (IF)
3 references available
Catalog no. ABIN361622
Quantity 50 ug  (0.5 mg/ml)
Price 627.13 $   Plus shipping costs $45.00
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anti-UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) antibody

anti-UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) antibody (2)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name UPF3A
Gene ID 65110
Immunogen Recombinant protein of full length Human UPF3A
Format Affinity-purified
Description Function: Part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. Involved innonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon junctions Subcellular location: Nucleus. Cytoplasm. Note: Shuttling between the nucleus and the cytoplasm Tissue specificity: Isoform 1 is strongly expressed in testis, uterus, muscle, fetal brain and spinal cord. Isoform 2 is strongly expressed infetal brain and spinal cord Sequence similarities: Belongs to the RENT3 family.

Application Details
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Application Notes WB: 1ug/ml. IF: 10ug/ml
Concentration 0.5 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Restrictions For Research Use only

Publications
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Serin, Gersappe, Black et al.: "Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)." in: Molecular and cellular biology, Vol. 21, Issue 1, pp. 209-23, 2001 (PubMed).

Lykke-Andersen, Shu, Steitz: "Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon." in: Cell, Vol. 103, Issue 7, pp. 1121-31, 2001 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A)", type "Antibodies"
Hosts Rabbit (9), Goat (2), Mouse (1)
Reactivities Human (10), Mouse (Murine) (3), Rat (Rattus) (3), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications Western Blotting (WB) (10), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunofluorescence (IF) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Epitopes Internal Region (2), Center (1)