Add to Basket
Order hotline:
 |
+1 404 474 4654 |
 |
+1 888 205 9894 (TF) |
UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) antibody
| Antigen | UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) |
| Synonyms | UPF3, HUPF3A, RENT3A, MGC151365, 2600001C03Rik, 4930546M19Rik, UPF3A, si:dkey-21o13.6 |
| Clonality | Polyclonal |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Immunofluorescence (IF)
|
 |
3 references available |
| Catalog no. | ABIN361622 |
| Quantity | 50 ug (0.5 mg/ml) |
| Price | 619.19 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | UPF3A |
| Gene ID | 65110 |
| Immunogen | Recombinant protein of full length Human UPF3A |
| Format | Affinity-purified |
| Description | Function: Part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. Involved innonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon junctions Subcellular location: Nucleus. Cytoplasm. Note: Shuttling between the nucleus and the cytoplasm Tissue specificity: Isoform 1 is strongly expressed in testis, uterus, muscle, fetal brain and spinal cord. Isoform 2 is strongly expressed infetal brain and spinal cord Sequence similarities: Belongs to the RENT3 family. |
Application Details
| Application Notes | WB: 1ug/ml. IF: 10ug/ml |
| Concentration | 0.5 mg/ml |
| Purification | Protein A purified |
| Buffer | PBS, pH 7.2 |
| Storage | Store below -20 degrees Celsius |
| Restrictions | For Research Use only |
Publications
| Publications |
Serin, Gersappe, Black et al.: "Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)." in: Molecular and cellular biology, Vol. 21, Issue 1, pp. 209-23, 2001 (PubMed).
Lykke-Andersen, Shu, Steitz: "Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon." in: Cell, Vol. 103, Issue 7, pp. 1121-31, 2001 (PubMed). Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed). |
Alternatives
Alternatives for antigen "UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A)", type "Antibodies"
| Hosts | Mouse (1), Rabbit (1) |
| Reactivities | Human (1) |
| Applications | Western Blotting (WB) (2), ELISA (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1) |
