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UPF3 Regulator of Nonsense Transcripts Homolog A (Yeast) (UPF3A) antibody

Details for Product No. ABIN361622
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Antigen
Synonyms UPF3, HUPF3A, RENT3A, 2600001C03Rik, 4930546M19Rik, UPF3A, si:dkey-21o13.6
Reactivity
Human
(11), (2), (2), (1)
Host
Mouse
(5), (5), (2)
Clonality
Polyclonal
Application
Western Blotting (WB), Immunofluorescence (IF)
(11), (7), (2), (2), (2)
Pubmed 3 references available
Quantity 50 µg
Shipping to United States (Change)
Availability Will be delivered in 9 to 11 Business Days
Catalog No. ABIN361622
627.13 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant protein of full length Human UPF3A
Purification Protein A purified
Alternative Name UPF3A
Background Function: Part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. Involved innonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon junctions Subcellular location: Nucleus. Cytoplasm. Note: Shuttling between the nucleus and the cytoplasm Tissue specificity: Isoform 1 is strongly expressed in testis, uterus, muscle, fetal brain and spinal cord. Isoform 2 is strongly expressed infetal brain and spinal cord Sequence similarities: Belongs to the RENT3 family.
Gene ID 65110
Application Notes WB: 1ug/ml. IF: 10ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS, pH 7.2
Storage -20 °C
General Serin, Gersappe, Black et al.: "Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)." in: Molecular and cellular biology, Vol. 21, Issue 1, pp. 209-23, 2001 (PubMed).

Lykke-Andersen, Shu, Steitz: "Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon." in: Cell, Vol. 103, Issue 7, pp. 1121-31, 2001 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Hosts (5), (5), (2)
Reactivities (11), (2), (2), (1)
Applications (11), (7), (2), (2), (2)
Epitopes (3), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN361622
627.13 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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