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Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1) antibody

Antigen

Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1)
Synonyms MMS4L, FLJ31364, gs125, FLJ00151, MGC106543, 6820428D13, EME1, fc30c07, wu:fc30c07, MGC147170
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Western Blotting (WB), Immunofluorescence (IF)
3 references available
Catalog no. ABIN361624
Quantity 50 ug  (0.5 mg/ml)
Price 619.19 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

anti-Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1) antibody

anti-Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1) antibody (2)

anti-Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1) antibody (3)

Additional Information
Application Details Publications Images Alternatives Secondary Antibodies back to top

Alternative name EME1
Gene ID 146956
Immunogen Recombinant protein of full length Human EME1
Format Affinity-purified
Description Function: Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structureswith a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be requiredin mitosis for the processing of stalled or collapsed replication forks Subcellular location: Nucleus > nucleolus. Note: Recruited to regions of DNA damage in S-phase cells Sequence similarities: Belongs to the EME1/MMS4 family.

Application Details
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Application Notes WB: 1ug/ml. IF: 10ug/ml
Concentration 0.5 mg/ml
Purification Protein A purified
Buffer PBS, pH 7.2
Storage Store below -20 degrees Celsius
Research Area Enzymes
Restrictions For Research Use only

Publications
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Publications O?sruenuc, Sancar: "Identification and characterization of human MUS81-MMS4 structure-specific endonuclease." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21715-20, 2003 (PubMed).

Ciccia, Constantinou, West: "Identification and characterization of the human mus81-eme1 endonuclease." in: The Journal of biological chemistry, Vol. 278, Issue 27, pp. 25172-8, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Alternatives
Application Details Publications Images Secondary Antibodies back to top

Alternatives for antigen "Essential Meiotic Endonuclease 1 Homolog 1 (S. Pombe) (EME1)", type "Antibodies"
Hosts Rabbit (26), Mouse (6)
Reactivities Human (29), Mouse (Murine) (18), Rat (Rattus) (17), Dog (Canine) (3), Pig (Porcine) (2), Rabbit (2), Cow (Bovine) (1), Horse (Equine) (1)
Applications Immunofluorescence (IF) (17), Flow Cytometry (FACS) (16), Western Blotting (WB) (15), ELISA (5), Enzyme Immunoassay (EIA) (3), ELISA (Detection) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes Center (1), N-Term (1)