Solute Carrier Family 29 (Nucleoside Transporters), Member 2 (SLC29A2) antibody

Antigen: Solute Carrier Family 29 (Nucleoside Transporters), Member 2 (SLC29A2)

Synonyms: ENT2, DER12, HNP36, Ent2, Der12, Hnp36, Slc29a2, MGC63618, ent2, der12, hnp36, MGC82995, MGC179613, DKFZp468L038

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN361625

Additional Information

Alternative name: SLC29A2

Gene ID: 3177

Immunogen: Recombinant protein of full length Human SLC29A2

Format: Affinity-purified

Description: Function: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Less sensitive thanSLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine Subcellular location: Isoform 1: Cell membrane, Multi-pass membrane protein. Isoform 2: Nucleus membrane, Multi-pass membraneprotein Tissue specificity: Expressed in placenta, brain, heart and ovarian tissues Sequence similarities: Belongs to the SLC29A transporter family.

Application Details

Application Notes: WB: 1ug/ml. IF: 10ug/ml

Concentration: 0.5 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Transporters

Restrictions: For Research Use only

Images

SLC29A2 transfected 293T cell lysate

HeLa cell 0 0

Publications

Publications: Williams, Lanahan: "A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein." in: Biochemical and biophysical research communications, Vol. 213, Issue 1, pp. 325-33, 1995 (PubMed).

Griffiths, Yao, Abidi et al.: "Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta." in: The Biochemical journal, Vol. 328 ( Pt 3), pp. 739-43, 1998 (PubMed).

Crawford, Patel, Naeve et al.: "Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 5288-93, 1998 (PubMed).