Nucleoporin 43kDa (NUP43) antibody

Antigen: Nucleoporin 43kDa (NUP43)

Synonyms: p42, FLJ13287, bA350J20.1, AA409950, 2610016K01Rik, 2610529I12Rik, MGC142987, MGC184722, MGC154553

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN361627

Additional Information

Alternative name: NUP43

Gene ID: 348995

Immunogen: Recombinant protein of full length Human NUP43

Format: Affinity-purified

Description: Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for theassembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitoticprogression and chromosome segregation Subcellular location: Kinetochore. Nucleus > nuclear pore complex Sequence similarities: Contains 6 WD repeats.

Application Details

Application Notes: WB: 1ug/ml. IF: 10ug/ml

Concentration: 0.5 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Transporters

Restrictions: For Research Use only

Images

NUP43 transfected 293T cell lysate

NUP43 transfected 293T cell lysate

HeLa cell 0

Publications

Cronshaw, Krutchinsky, Zhang et al.: "Proteomic analysis of the mammalian nuclear pore complex." in: The Journal of cell biology, Vol. 158, Issue 5, pp. 915-27, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Louiodice, Alves, Rabut et al.: "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis." in: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3333-44, 2004 (PubMed).