General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2) antibody

Antigen: General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2)

Synonyms: KIAA0011, TFIIIC110, TFIIIC-BETA, GTF3C2, MGC155253, TF3C-beta, DKFZp469M0113

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN361632

Additional Information

Alternative name: GTF3C2

Gene ID: 2976

Immunogen: Recombinant protein of full length Human GTF3C2

Format: Affinity-purified

Description: Function: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly ontRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizinginteractions of TFIIIC2 with TFIIIC1 Subcellular location: Nucleus Sequence similarities: Contains 4 WD repeats.

Application Details

Application Notes: WB: 1ug/ml. IF: 10ug/ml

Concentration: 0.5 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Restrictions: For Research Use only

Images

GTF3C2 transfected 293T cell lysate

GTF3C2 transfected 293T cell lysate

HeLa cell 0

Publications

Nomura, Miyajima, Sazuka et al.: "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 1, Issue 1, pp. 27-35, 1995 (PubMed).

Sinn, Wang, Kovelman et al.: "Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors." in: Genes & development, Vol. 9, Issue 6, pp. 675-85, 1995 (PubMed).