G Protein-Coupled Receptor, Family C, Group 5, Member C (GPRC5C) antibody

Antigen: G Protein-Coupled Receptor, Family C, Group 5, Member C (GPRC5C)

Synonyms: RAIG3, RAIG-3, MGC131820, Raig3, MGC6786, MGC11976, 1110028I06Rik, 3200002M13Rik, GPRC5C, zgc:171736

Clonality: Polyclonal

Host: Mouse

Reactivity: Human

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Catalog no.: ABIN361638

Additional Information

Alternative name: GPRC5C

Gene ID: 55890

Immunogen: Recombinant protein of full length Human GPRC5C

Format: Affinity-purified

Description: Function: This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-proteinsignaling pathways Subcellular location: Cell membrane, Multi-pass membrane protein. Cytoplasmic vesicle membrane, Multi-pass membrane protein. Note:Localized in the plasma membrane and perinuclear vesicles Tissue specificity: Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. Inbrain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia(DRG) Sequence similarities: Belongs to the G-protein coupled receptor 3 family.

Application Details

Application Notes: WB: 1ug/ml. FACS: 1ug/ml. IF: 1ug/ml

Concentration: 1 mg/ml

Purification: Protein A purified

Buffer: PBS, pH 7.2

Storage: Store below -20 degrees Celsius

Research Area: Signaling

Restrictions: For Research Use only

Images

GPRC5C transfected 293T cell lysate. Negative control Transfectant

293 cell

GPRC5C expressing 293 cells 0

Publications

Publications: Robbins, Michalovich, Hill et al.: "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)." in: Genomics, Vol. 67, Issue 1, pp. 8-18, 2000 (PubMed).

Braeuner-Osborne, Jensen, Sheppard et al.: "Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D." in: Biochimica et biophysica acta, Vol. 1518, Issue 3, pp. 237-48, 2001 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).