ING1 antibody (N-Term)
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- Target See all ING1 Antibodies
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ING1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~33 kDa.
- Cross-Reactivity
- Human, Mouse
- Purification
- Peptide Affinity Purified
- Immunogen
- Mouse p33 ING1 N-terminal peptide -KLH conjugates
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:50)
- optimal dilutions for assays should be determined by the user.
- Comment
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0.25 mg/ml was sufficient for detection of ABIN361701 in lysates prepared from human melanoma cell lines by western blot analysis.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- TBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- Alternative Name
- ING1 (ING1 Products)
- Synonyms
- p24ING1c antibody, p33 antibody, p33ING1 antibody, p33ING1b antibody, p47 antibody, p47ING1a antibody, p33ING1c antibody, zgc:136918 antibody, ING1 antibody, 2610028J21Rik antibody, AA407184 antibody, AI875420 antibody, mING1h antibody, p33Ing1 antibody, p37Ing1b antibody, xing1 antibody, inhibitor of growth family member 1 antibody, inhibitor of growth family, member 1 antibody, inhibitor of growth family member 1 S homeolog antibody, ING1 antibody, Ing1 antibody, ing1 antibody, ing1.S antibody
- Background
- The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemo sensitivity (1-4). It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus (5). It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) (6, 7). ING1 can possibly influence the above biological functions depending on which variant is expressed (1-4).
- Gene ID
- 26356
- NCBI Accession
- NP_036049
- UniProt
- Q9QXV3
- Pathways
- Protein targeting to Nucleus, Autophagy
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