Cav Beta1 antibody

Antigen: Cav Beta1

Clonality: Monoclonal (S7-18)

Host: Mouse

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Catalog no.: ABIN361776

Additional Information

Immunogen: Synthetic peptide amino acids 19-34 of rat CavB1, accession number NP_059042

Format: Protein G purified

Isotype: IgG1  (Matching secondary antibodies)

Clone: S7-18

Description: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane.

Specificity: ~80, 55 kDa. No cross reactivity against Cav

Application Details

Application Notes: WB: 1-10ug/mL (if results are off, try using the lysate without boiling), IHC/ICC: 0.1-1.0ug/mL (Perox), 1.0-10ug/mL (IF)

Concentration: 1mg/mL

Buffer: Protein G Purified. In PBS pH7.4, 50% glycerol and 0.09% sodium azide.

Storage: -20°C, 1 year+, shipped on cold packs or ambient

Restrictions: For Research Use only

Images

CavBeta1 (S7-18), Human Hippocampus

Publications

Publications: Leyris, Gondeau, Charnet et al.: "RGK GTPase-dependent CaV2.1 Ca2+ channel inhibition is independent of CaVbeta-subunit-induced current potentiation." in: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2627-38, 2009 (PubMed).