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Crystallin, alpha B (CRYAB) antibody

Antigen

Crystallin, alpha B (CRYAB)
Synonyms CRYA2, CTPP2, HSPB5, Crya2, HspB5, Crya-2, AACRYA, CRYAB, DKFZp468D2015, Cryab
Clonality Monoclonal (1A7-D5)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Cow (Bovine)
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN361809
Quantity 200ug  (1mg/mL)  (Variants)
Price 295.00 $   Plus shipping costs $35.00
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anti-Crystallin, alpha B (CRYAB) antibody

Additional Information
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Alternative name Alpha B Crystallin
Immunogen Native Alpha B Crystallin
Format Protein G purified
Isotype IgG1  (Matching secondary antibodies)
Clone 1A7-D5
Description The alpha-crystallins are major water-soluble lens structural proteins of the vertebrate eye that are related to the small heat shock protein family. The alpha-crystallins possess structural and functional similarities with Hsp25 and Hsp27 (1). Mammalian lens cystallins are divided into alpha, beta and gamma families. Alpha and beta families are further divided into acidic and basic groups (Alpha-A and Alpha-B respectively). In the lens, alpha-crystallin primarily functions to maintain proper refractive index, however it can also function as a molecular chaperone that binds to the denatured proteins, keeping them in solution and thereby maintaining the translucency of the lens. When cellular stress occurs, alpha-crystallin enters its
Specificity Detects a band at ~20kDa (Predicted mol. weight is ~21kDa) corresponding to alpha B crystallin. Does not cross react with alpha A crystallin, beta-L crystallin, Beta-H crystallin, gamma crystallin, Hsp25, Hsp27 or Hsp47 proteins. Species cross-reactivity: Human, Bovine.

Application Details
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Application Notes 1/2000 for WB
Concentration 1mg/mL
Buffer PBS pH 7.2, 50% glycerol, 0.09% azide. Protein G affinity purified.
Storage -20°C, 1 year+, shipped on cold packs or ambient
Research Area Cancer, Tyrosine Kinases
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies Variants back to top

Alternatives for antigen "Crystallin, alpha B (CRYAB)", type "Antibodies"
Hosts Mouse (46), Rabbit (30), Goat (3)
Reactivities Human (69), Mouse (Murine) (28), Rat (Rattus) (23), Cow (Bovine) (19), Chicken (5), Monkey (1)
Applications Western Blotting (WB) (72), ELISA (26), Immunohistochemistry (IHC) (23), Enzyme Immunoassay (EIA) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Immunofluorescence (IF) (11), Immunocytochemistry (ICC) (5), Flow Cytometry (FACS) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1)
Epitopes pSer19 (2), pSer45 (2), pSer59 (2), Ab-19 (1), Ab-45 (1), Ab-59 (1)